I am in the design stages of a monocoque frame as well as engine (just the crankcase), and transmission. My design is technically a semi-monocoque as it uses tubes, stressed panels, and the crankcase as the load bearing members. The crank case also forms the front bulkhead for the control arms (Hossack front end). Right now I am a little hung up on the power transfer aspect of the project, specifically finding OEM transmission internals that can be adapted to my engine design. The engine is a 300cc triple, should make right around 100hp, but will require pretty high RPM to get there, something like 17k-18k. Unfortunately the monocque is mostly a collection of sketches at this point, but I have been actively getting the crankcase into CAD and have it fairly close as far as the function of the engine is concerned anyways. I believe it to be machinable on my machine as well (harder than you might think with 3 axis). It's a big project that's going to take quite a while, I already have many months just in the conceptual part of the project and have hardly begun sussing out the true details. The financial burden is probably the biggest issue. It's hard to invest in raw aluminum and tooling when the family needs to food.